| Friday 19 October 2018 | 1 | x | 2 |
| 20:30 | Club Brugge vs Waasland-Beveren | 0.20 | 5.25 | 9.00 | +73 |
| Saturday 20 October 2018 | 1 | x | 2 |
| 18:00 | Royal Mouscron vs Standard Liege | 4.00 | 3.00 | 0.55 | +73 |
| 20:00 | KV Kortrijk vs St. Truidense VV | 1.20 | 2.35 | 1.85 | +73 |
| 20:00 | Royal Antwerp FC vs Sporting Lokeren | 0.35 | 3.45 | 6.50 | +73 |
| 20:30 | KRC Genk vs AS Eupen | 0.16 | 5.50 | 10.00 | +73 |
| Sunday 21 October 2018 | 1 | x | 2 |
| 14:30 | Anderlecht vs Cercle Brugge | 0.35 | 3.70 | 5.50 | +73 |
| 18:00 | KV Oostende vs KAA Gent | 2.05 | 2.40 | 1.10 | +73 |
| 20:00 | Royal Charleroi SC vs SV Zulte Waregem | 0.85 | 2.50 | 2.65 | +73 |
